The Other Side of Yew

By Erin Holden

As an herbalist I’m interested in many aspects of plants – from their use in herbal and conventional medicine, to lore that informs us how those in the past viewed the plant. I knew that Taxol was a cancer drug made from the yew tree, but when a friend mentioned its poisonous aspects, I decided to dig a bit deeper.

Taxol, the well-known cancer treatment, was first isolated and studied in the early 1960s into the late 1970s, and approved as a cancer drug in the early 1990s. Paclitaxel, the common chemical name of Taxol, was initially extracted from the bark of the Pacific yew (Taxus brevifolia). It was quickly realized that extracting enough paclitaxel to meet demand would wipe out this species in short order, so scientists turned to its faster-growing cousin, the European yew (Taxus baccata), as an alternative. A precursor…